{"id":462,"date":"2020-05-13T10:21:38","date_gmt":"2020-05-13T10:21:38","guid":{"rendered":"https:\/\/www.l2mtech.de\/?page_id=462"},"modified":"2020-08-02T05:14:06","modified_gmt":"2020-08-02T05:14:06","slug":"pearlflow","status":"publish","type":"page","link":"https:\/\/www.l2mtech.de\/?page_id=462","title":{"rendered":"PearlFlow"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]<\/p>\n

Paclitaxel Eluting Peripheral Drug Coated Balloon Dilatation Catheter<\/p><\/blockquote>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1591609204230{margin-top: 25px !important;padding-top: 15px !important;padding-bottom: 15px !important;background-color: #e8e8e8 !important;}”][vc_column width=”1\/2″][vc_column_text]<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Pearl Flow :Peripheral Drug Coated Balloon<\/span><\/td>\n<\/td>\nSpecifications<\/span><\/td>\n<\/tr>\n
USABLE LENGTH<\/td>\n<\/td>\n138 cm<\/td>\n<\/tr>\n
LENGTH OF GUIDE WIRE LUMEN<\/td>\n<\/td>\n127 cm<\/td>\n<\/tr>\n
MATERIAL<\/td>\nBalloon<\/td>\nProprietary polyamide compound<\/td>\n<\/tr>\n
Distal shaft<\/td>\nPolyamide, multilayer tubing<\/td>\n<\/tr>\n
Proximal shaft<\/td>\nStainless steel, PTFE coated<\/td>\n<\/tr>\n
SHAFT SIZE<\/td>\nProximal<\/td>\n1.9 F<\/td>\n<\/tr>\n
Distal<\/td>\n2.8 F<\/td>\n<\/tr>\n
BALLOON FOLDING<\/td>\n<\/td>\n3-fold balloon<\/td>\n<\/tr>\n
MARKER BANDS<\/td>\n<\/td>\nEmbedded Platinum \/ Iridium marker<\/td>\n<\/tr>\n
TIP PROFILE<\/td>\n<\/td>\n0.017″ (0.43 mm)<\/td>\n<\/tr>\n
MAX. RECOMMENDED GUIDE WIRE<\/td>\n<\/td>\n0.014″ (0.36 mm)<\/td>\n<\/tr>\n
RECOMMENDED GUIDING CATHETER<\/td>\nmin. ID<\/td>\n5 F \/ 0.056″ (1,65 mm)<\/td>\n<\/tr>\n
Usable Catheter length<\/td>\n<\/td>\n85cm \/ 150cm<\/td>\n<\/tr>\n
Material<\/td>\nBalloon<\/td>\nPolyamide<\/td>\n<\/tr>\n
<\/td>\nShaft<\/td>\nPolyamide, Dual lumen tubing<\/td>\n<\/tr>\n
X-ray marker<\/td>\n<\/td>\nPlatinum-Iridium<\/td>\n<\/tr>\n
Catheter design<\/td>\n<\/td>\nOTW – over the wire<\/td>\n<\/tr>\n
Introducer set<\/td>\n<\/td>\n4 F<\/td>\n<\/tr>\n
Catheter<\/td>\n<\/td>\n4 F catheter<\/td>\n<\/tr>\n
Max. recommended guide wire<\/td>\n<\/td>\n0.018″<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/2″][vc_column_text]Coating:<\/p>\n\n\n\n\n\n\n
DRUG (API)<\/td>\nPaclitaxel<\/td>\n<\/tr>\n
DOSAGE<\/td>\n3,0\u03bcg\/mm2<\/td>\n<\/tr>\n
TRANSFER MATRIX (Exipient)<\/td>\nButyryl-tri-hexyl citrate (BTHC)<\/td>\n<\/tr>\n
COATED AREA<\/td>\nCylinder and tapered sections of the balloon<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

[\/vc_column_text][vc_single_image image=”655″ img_size=”500×250″ alignment=”center” style=”vc_box_rounded” onclick=”link_image” css_animation=”bounceIn”][vc_column_text]<\/p>\n

In peripheral artery disease, DCB therapy has proven superior to balloon angioplasty for treatment of de novo femoropopliteal and below-the-knee disease.<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”The Excipient” font_container=”tag:h4|text_align:left” use_theme_fonts=”yes”][vc_column_text]The excipient is a crucial part of a drug-eluting balloon, as it may have a direct effect on the drug uptake. The rationale behind a higher drug uptake lies in the effect of the excipient.<\/p>\n

Another benefit of excipients may be the smooth dispersion of the drug in the excipient matrix increasing the uptake[\/vc_column_text][vc_row_inner][vc_column_inner width=”1\/2″][vc_column_text]Why Butyryl-tri-hexyl citrate (BTHC) coating?<\/strong><\/span><\/p>\n

    \n
  • Proven Track record<\/li>\n
  • Keeps Paclitaxel in microcrystalline structure<\/li>\n
  • Degrades to Citric acid and alcohol and metabolized rapidly.<\/li>\n
  • BTHC coating is less soluble than hydrophilic alternatives resulting in more bio-availability of the drug<\/li>\n<\/ul>\n

    [\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/2″][vc_column_text]Balloon Compliance Chart:<\/strong><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    <\/td>\nBalloon-\u00d8 [mm] 4,00 5,00<\/td>\n<\/tr>\n
    2.00<\/td>\n2.50<\/td>\n3.00<\/td>\n4.00<\/td>\n5.00<\/td>\n6.00<\/td>\n7.00<\/td>\n<\/tr>\n
    Pressure-
    \n[MPa\/atm ]<\/td>\n    		0.7 \/ 7<\/td>\n2.00<\/td>\n2.50<\/td>\n3.00<\/td>\n4.00<\/td>\n5.00<\/td>\n6.00<\/td>\n7.00<\/td>\n<\/tr>\n
    0.8 \/ 8<\/td>\n2.04<\/td>\n2.53<\/td>\n3.03<\/td>\n4.06<\/td>\n5.11<\/td>\n6.08<\/td>\n7.05<\/td>\n<\/tr>\n
    0.9 \/ 9<\/td>\n2.09<\/td>\n2.57<\/td>\n3.05<\/td>\n4.12<\/td>\n5.22<\/td>\n6.15<\/td>\n7.10<\/td>\n<\/tr>\n
    1.0 \/ 10<\/td>\n2.13<\/td>\n2.60<\/td>\n3.08<\/td>\n4.18<\/td>\n5.32<\/td>\n6.23<\/td>\n7.15<\/td>\n<\/tr>\n
    1.1 \/ 11<\/td>\n2.18<\/td>\n2.63<\/td>\n3.10<\/td>\n4.24<\/td>\n5.43<\/td>\n6.30<\/td>\n7.20<\/td>\n<\/tr>\n
    1.2 \/ 12<\/td>\n2.22<\/td>\n2.67<\/td>\n3.13<\/td>\n4.30<\/td>\n5.54<\/td>\n6.38<\/td>\n7.25<\/td>\n<\/tr>\n
    1.3 \/ 13<\/td>\n2.27<\/td>\n2.70<\/td>\n3.15<\/td>\n4.36<\/td>\n5.65<\/td>\n6.45<\/td>\n7.30<\/td>\n<\/tr>\n
    1.4 \/ 14<\/td>\n2.31<\/td>\n2.73<\/td>\n3.18<\/td>\n4.42<\/td>\n5.76<\/td>\n6.53<\/td>\n<\/td>\n<\/tr>\n
    1.5 \/ 15<\/td>\n2.35<\/td>\n2.77<\/td>\n3.20<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
    <\/td>\nNOMINAL PRESSURE 0.7 MPa \/ 7 atm<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
    <\/td>\nRBP (Rated Burst Pressure)<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    [\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row full_width=”stretch_row_content” gap=”20″ css=”.vc_custom_1591612298236{margin-top: 20px !important;padding-top: 15px !important;padding-bottom: 15px !important;background-color: #e8e8e8 !important;}”][vc_column width=”1\/2″][vc_column_text]<\/p>\n\n\n\n
    Ordering Information:PearlFlow (0.018″ Guide Wire \/ Shaft Length 85cm)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
    Balloon-\u00d8<\/td>\nBalloon Length<\/td>\n<\/tr>\n
    40 mm<\/td>\n\u00a060 mm<\/td>\n80 mm<\/td>\n120 mm<\/td>\n150 mm<\/td>\n<\/tr>\n
    2.00 mm<\/td>\nPFM2000400
    \n85<\/td>\n    		PFM2000600
    \n85<\/td>\n    		PFM2000800
    \n85<\/td>\n    		PFM20001200
    \n85<\/td>\n    		PFM20001500
    \n85<\/td>\n<\/tr>\n
    2.50 mm<\/td>\nPFM2500400
    \n85<\/td>\n    		PFM2500600
    \n85<\/td>\n    		PFM2500800
    \n85<\/td>\n    		PFM25001200
    \n85<\/td>\n    		PFM25001500
    \n85<\/td>\n<\/tr>\n
    3.00 mm<\/td>\nPFM3000400
    \n85<\/td>\n    		PFM3000600
    \n85<\/td>\n    		PFM3000800
    \n85<\/td>\n    		PFM30001200
    \n85<\/td>\n    		PFM30001500
    \n85<\/td>\n<\/tr>\n
    4.00 mm<\/td>\nPFM4000400
    \n85<\/td>\n    		PFM4000600
    \n85<\/td>\n    		PFM4000800
    \n85<\/td>\n    		PFM40001200
    \n85<\/td>\n    		PFM40001500
    \n85<\/td>\n<\/tr>\n
    5.00 mm<\/td>\nPFM5000400
    \n85<\/td>\n    		PFM5000600
    \n85<\/td>\n    		PFM5000800
    \n85<\/td>\n    		PFM50001200
    \n85<\/td>\n    		PFM50001500
    \n85<\/td>\n<\/tr>\n
    6.00 mm<\/td>\nPFM6000400
    \n85<\/td>\n    		PFM6000600
    \n85<\/td>\n    		PFM6000800
    \n85<\/td>\n    		PFM60001200
    \n85<\/td>\n    		PFM60001500
    \n85<\/td>\n<\/tr>\n
    7.00 mm<\/td>\nPFM7000400
    \n85<\/td>\n    		PFM7000600
    \n85<\/td>\n    		PFM7000800
    \n85<\/td>\n    		PFM70001200
    \n85<\/td>\n    		PFM70001500
    \n85<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    [\/vc_column_text][\/vc_column][vc_column width=”1\/2″][vc_column_text]<\/p>\n\n\n\n
    Ordering Information:PearlFlow (0.018″ Guide Wire \/ Shaft Length 150cm)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n\n\n\n\n\n\n
    Balloon-\u00d8<\/td>\nBalloon Length<\/td>\n<\/tr>\n
    40 mm<\/td>\n\u00a060 mm<\/td>\n80 mm<\/td>\n120 mm<\/td>\n150 mm<\/td>\n<\/tr>\n
    2.00 mm<\/td>\nPFM2000400
    \n150<\/td>\n    		PFM2000600
    \n150<\/td>\n    		PFM2000800
    \n150<\/td>\n    		PFM20001200
    \n150<\/td>\n    		PFM20001500
    \n150<\/td>\n<\/tr>\n
    2.50 mm<\/td>\nPFM2500400
    \n150<\/td>\n    		PFM2500600
    \n150<\/td>\n    		PFM2500800
    \n150<\/td>\n    		PFM25001200
    \n150<\/td>\n    		PFM25001500
    \n150<\/td>\n<\/tr>\n
    3.00 mm<\/td>\nPFM3000400
    \n150<\/td>\n    		PFM3000600
    \n150<\/td>\n    		PFM3000800
    \n150<\/td>\n    		PFM30001200
    \n150<\/td>\n    		PFM30001500
    \n150<\/td>\n<\/tr>\n
    4.00 mm<\/td>\nPFM4000400
    \n150<\/td>\n    		PFM4000600
    \n150<\/td>\n    		PFM4000800
    \n150<\/td>\n    		PFM40001200
    \n150<\/td>\n    		PFM40001500
    \n150<\/td>\n<\/tr>\n
    5.00 mm<\/td>\nPFM5000400
    \n150<\/td>\n    		PFM5000600
    \n150<\/td>\n    		PFM5000800
    \n150<\/td>\n    		PFM50001200
    \n150<\/td>\n    		PFM50001500
    \n150<\/td>\n<\/tr>\n
    6.00 mm<\/td>\nPFM6000400
    \n150<\/td>\n    		PFM6000600
    \n150<\/td>\n    		PFM6000800
    \n150<\/td>\n    		PFM60001200
    \n150<\/td>\n    		PFM60001500
    \n150<\/td>\n<\/tr>\n
    7.00 mm<\/td>\nPFM7000400
    \n150<\/td>\n    		PFM7000600
    \n150<\/td>\n    		PFM7000800
    \n150<\/td>\n    		PFM70001200
    \n150<\/td>\n    		PFM70001500
    \n150<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    [\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

    [vc_row][vc_column][vc_column_text] Paclitaxel Eluting Peripheral Drug Coated Balloon Dilatation Catheter [\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row” css=”.vc_custom_1591609204230{margin-top: 25px !important;padding-top: 15px !important;padding-bottom: 15px !important;background-color: #e8e8e8 !important;}”][vc_column width=”1\/2″][vc_column_text] Pearl Flow :Peripheral Drug Coated Balloon Specifications USABLE LENGTH 138 cm LENGTH OF GUIDE WIRE LUMEN 127 cm MATERIAL Balloon Proprietary polyamide compound Distal shaft Polyamide, multilayer tubing Proximal shaft Stainless steel, PTFE coated<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":40,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/pages\/462"}],"collection":[{"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=462"}],"version-history":[{"count":26,"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/pages\/462\/revisions"}],"predecessor-version":[{"id":673,"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/pages\/462\/revisions\/673"}],"up":[{"embeddable":true,"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=\/wp\/v2\/pages\/40"}],"wp:attachment":[{"href":"https:\/\/www.l2mtech.de\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}